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医学翻译-妇科翻译作品展示

发布者:鑫达医学翻译公司 发布时间:2011-08-09阅读:

原文:
The fluid which surrounds the developing embryo/fetus is initially very similar in composition to extracellular fluid of the fetus, and may well arise as a transudate across fetal skin before keratinisation occurs. Subsequently there is an increase in volume, accompanied in the human and sheep (but not mouse) by a decrease in osmolality, but at the same time an increase in the concentrations of urea and creatinine. The major inputs to amniotic fluid are lung liquid and fetal urine. It has been well demonstrated that fetal urine becomes increasingly hypotonic to fetal plasma as gestation progresses in both human and sheep, due to both a relatively large glomerular filtration rate for renal blood flow in the fetal metanephros, and to the relatively slow acquisition of AQP2 in the fetal kidney. What is of prime importance to note is that AF composition appears to be under much tighter control that AF volume. Abnormalities of composition are much rarer than those of volume, and in most cases of abnormality of volume, whether too little (olighydramnios) or too much (polyhydramnios), the compositon is normal for the gestational age. Quantitatively the fetal urine is the largest input into the amniotic fluid cavity (up to 2.5 l/day in a human/sheep fetus at 4 kg) and it is the most important contributor to composition. This can be seen from the facts, as set out in Table 1, that AF osmolality decreases with the increasing volumes of dilute fetal urine input, in sheep and human, rather that following maternal plasma composition.


译文:
发育胚胎、胎儿周围的液体与胎儿细胞外液成分相似,可能为胎儿皮肤角化前的渗出液。 随后,羊水量增加,并伴有渗透压降低(人与绵羊体内),同时尿素与肌酸酐浓度增加。 流入羊水的主要是肺部液体与胎尿。已证实人与绵羊妊娠期内胎尿渗透压逐渐降低,并最终低于胎儿血浆的渗透压,原因为胎儿后肾血流的肾小球滤过率相对较高,且胎儿肾脏内AQP2的俘获率较低。需注意的是AF组成似乎受AF量的严格控制。羊水成分异常较罕见,即便在多数AF量异常(如羊水过少或过多)的情况下羊水成分依然维持正常。胎尿为羊水腔液体输入最大贡献者(体重为4kg的人或绵羊每天多达2.5L),因此对羊水成分的影响最大。自表1可以看出:稀释胎尿输入量增加可导致人、绵羊羊水渗透压降低,而母体血浆成分对其没有影响。


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