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血液学翻译

发布者:鑫达医学翻译 发布时间:2013-05-06阅读:

原文
本项研究共入选COPD患者66例,AECOPD组20例,AECOPD合并OSAHS组24例,COPD稳定期组22例,正常对照组10例。夜间睡眠监测显示COPD各组患者夜间睡眠呼吸紊乱均以低通气为主,HI/RDI%均高于对照组, 而OS组、AECOPD组、COPD稳定期组间均有差异,具有统计学意义(P<0.001)。 各组COPD患者夜间睡眠状态LSaO2 、MSaO2较清醒状态SaO2明显下降,差异有统计学意义(P<0.05),出现夜间低氧血症。其中OS组夜间LSaO2 、MSaO2明显低于AECOPD组、COPD稳定期组;AECOPD组低于COPD稳定期组,差异有统计学意义(P<0.05),提示OS组夜间低氧最为严重。SLT90%值OS组明显高于AECOPD组、COPD稳定期组,而AECOPD组高于COPD稳定期组,但两组均高于正常对照组,差异有统计学意义(P<0.05)。66例COPD患者肺功能障碍轻度23例,中度22例,重度21例,其中重度肺功能损害的COPD患者夜间血氧降低明显高于轻度、中度肺功能损害者,差异有统计学意义(P<0.05)。

译文
Sixty-six patients were divided into AECOPD group (n=20), AECOPD plus OSAHS group (n=24), stable COPD group (n=22), and control group (n=20). Polysomnography system indicated that the nocturnal sleep breathing disturbance was featured by hypopnea in COPD patients, and the HI/RDI% was higher than that of the control group. Statistical difference was detected between OS group, AECOPD group, stable COPD group (P<0.001). Remarkable decrease was detected in nocturnal LSaO2 and MSaO2 compared with waking SaO2 (P<0.05). Patients in each COPD group showed hyoxemia. Nocturnal LSaO2 and MSaO2 in OS group were lower than that of AECOPD group and stable COPD group. In addition, the LSaO2 and MSaO2 in AECOPD group was lower than that of stable COPD group (P<0.05). All these demonstrated nocturnal hypoxia was severe in OS patient. The SLT 90% of patients in OS group was higher than that of AECOPD group and stable COPD group. The SLT 90% of patients in AECOPD group was higher than that of stable COPD group, and the SLT 90% of both groups were higher than those of control groups (P<0.05). Among the 66 patients, the number of patients with mild, moderate and severe pulmonary function disorders was 23, 22 and 21, respectively. The nocturnal blood oxygen of COPD patients with severe pulmonary function disorders was higher than that of patients with mild and moderate pulmonary function disorders (P<0.05). 


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