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药学翻译-不良反应

发布者:鑫达医学翻译 发布时间:2013-07-08 8:50:52 阅读:

原文

In this study, the adverse event of oral system was set as the dependent variable Y. additionally, a series of variables including age (X1), gender (X2), smoking (X3), alcohol (X4), history of allergy (X5), original disease (X6), incorporation of other diseases (X7), applied medication (X8), and simultaneous medication (X9) were set as the independent variables. For X1, those ranged from 0~15 yrs, 16~ 30 yrs, 31~45yrs, 46~60 yrs, and ≥ 60 yrs were assigned with a score of 0, 1, 2, 3, and 4, respectively. For X2, the male patients were assigned a score of 0, while the female patients were assigned a score of 1. For X3, those with and without histories of smoking were assigned a score of 1 and 0, respectively. For X4, those with and without histories of drinking were assigned a score of 1 and 0, respectively. For X5, the original disease resulted in oral cavity lesion was assigned a score of 1 point. For those the original disease resulted in no oral cavity lesion was assigned a score of 0 point. For X7, those without incorporation of other disease were assigned a score of 0. Those with incorporation of other disease resulted in oral cavity lesion were assigned a score of 1, while those incorporation of other disease resulted in no oral cavity lesion were assigned a score of 2. For X8, those taken the drugs resulted in oral cavity lesion were assigned a score of 1, while those taken the drugs resulted in no oral cavity lesion were assigned a score of 0. For X9, those without simultaneous medication were assigned a score of 0. Those taken simultaneous medication resulted in oral cavity lesion were assigned a score of 1, while those taken the simultaneous medication resulted in no oral cavity lesion were assigned a score of 0. 

译文

以同时期发生的20600例药品不良反应进行统计,将发生口腔系统不良反应赋值为“1”,发生其他系统的不良反应赋值为“0”。 自变量X1的赋值是根据年龄分布:0-15岁、16-30岁、31-45岁、46-60岁、﹥60岁,分别赋值为“0、1、2、3、4”; 性别X2的赋值为,男性赋值为“0”,女性赋值为“1”;有既往吸烟史赋值为“1”、未有既往吸烟史赋值为“0”、 有既往饮酒史赋值为“1”、未有既往饮酒史赋值为“0”、原患疾病会造成口腔系统不良损害赋值为“1”、 原患疾病会造成口腔系统不良损害赋值为“0”、未合并疾病赋值为“0”、合并疾病对口腔系统造成不良损害赋值为“1”、合并疾病未造成口腔系统不良损害赋值为“2”、使用的药物有已知的口腔系统不良损害赋值为“1”、使用的药物没有已知的对口腔系统不良损害赋值为“0”、未合并用药赋值为“0”、合并用药有已知的口腔系统不良损害赋值为“1”、合并用药没有已知的口腔系统不良损害赋值为“2”。用Stata11.0软件包中Binary Logistic 自带的向前进入法进行多因素的Logistic 回归分析。


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