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医学翻译-血管科翻译

发布者:鑫达医学翻译公司 发布时间:2011-10-17 8:50:52 阅读:

原文:
Obesity is common in middle-aged Americans, especially in those in whom hypertension develops. Many epidemiologic studies have shown a strong correlation between obesity and hypertension. Data from the Nutritional Health and Nutritional Examination Survey (NHANES) show a remarkable and linear relation between the increase in body mass index (BMI) and systolic, diastolic, and pulse pressure among the United States population. The age-adjusted prevalence of hypertension in obese adult (BMI, 30 or more) is 41.9% for men and 37.8% for women. In regression models corrected for age-related increase in blood pressure, this relates toa BMI gain of 1.7 kg/rn2 in men and 1.25 kg/rn2 in women or an increase in- waist circumference of 4.5 cm for men and 2.5 cm for women or an increase in systolic blood pressure of 1 mm Hg. In the Framingham Heart Study, nearly 70% of newly acquired hypertension was attributed to prior obesity; 78% and 65% account for essential hypertension in men and women, respectively. It is alleged that truncal obesity (considered a better indicator of visceral adiposity) is more deleterious to the CV system than is generalized subcutaneous adiposity. The mechanism whereby obesity is related to elevated blood pressure is not well understood, but it remains a widely accepted risk factor for the development of hypertension. Of importance is that the deleterious effects of adiposity can be improved with weight loss of only a few pounds.

译文:
多数中年美国公民患有肥胖症,尤其是患有高血压的人群。很多流行病学研究表明肥胖症与高血压密切相关。全国健康与营养检查调查数据显示美国人民人体质量指数增加与收缩压、舒张压及脉搏压有明显的线性关系。男性成年肥胖者(人体质量指数≥30)年龄相关的高血压发病率为41.9%,女性发病率为37.8%。在年龄相关的血压升高回归模型中,男女性人体质量指数分别增加1.7 kg/m2、1.25 kg/m2,或男性腰围增加4.5厘米,女性腰围增加2.5厘米,或者收缩压增加1毫米汞柱。弗明汉心脏病研究中,约70%的初患高血压的患者先前患有肥胖症,其中男女原发性高血压所占的比例分别为78%、65%。躯干性肥胖(内脏肥胖的指证)比泛指的皮下肥胖对神经系统的损伤更为严重。肥胖与血压升高之间的机制尚未得知,但已经普遍认为肥胖是引发高血压的主要危险因子。重要的是体重降低几磅是否能改善肥胖的有害作用。
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