医学翻译样例

原文：
gd T cells  are  an important source of IL-17 upon high dose intratracheal BCG infection and low   dose Mtb aerosol infection. In  the BCG model, both IL-17  and gd  T cell deficient mice show delayed granuloma formation, suggesting that gd T cell-derived IL-17 is essential for initial granuloma organiza- tion, probably by promoting early neutrophil recruitment. However, unlike in the BCG model, low  dose aerosol Mtb  infected gd  T  cell   deficient  mice  display  enhanced  cellular  foci   with elevated accumulation of neutrophils. Antibody neutrali- zation  of  neutrophils  in   these  mice reduces  this  exacerbated accumulation of cells further supporting the hypothesis that neutrophil accumulation promotes granuloma formation in  the presence or  absence of  gd  T  cells.   Taken together, these data suggest a differential role  for IL-17 producing gd T cells  in the low dose aerosol Mtb   infection model versus the high dose intra-tracheal BCG model. Although initial cellular foci  organization seems  to   be   promoted  by   early neutrophil migration further research is  required to  understand the role  of  gd T cells  in  this process.

译文：
高剂量BCG感染或低剂量Mtb感染下，IL-17的重要来源均为γδT细胞。BCG模型中，IL-17与γδT缺陷小鼠肉芽肿形成延迟，表明γδT细胞来源的IL-17为肉芽肿形成的重要因素。该现象可能与促进早期嗜中性粒细胞招募相关。低剂量Mtb感染的γδT细胞缺陷小鼠细胞病灶内中性粒细胞积累量有所升高。嗜中性粒细胞抗体中和可降低细胞内嗜中性粒细胞积累，据此可推测嗜中性粒细胞积累可促进肉芽肿形成。这些表明，低剂量Mtb感染动物模型与高剂量BCG模型相比，产生IL-17的γδT细胞作用不同。 虽然早期嗜中性粒细胞前移可促进初期细胞病灶结构变化，但是要明确其中γδT细胞的作用还需要进一步研究。