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医疗器械之支架相关翻译

发布者:鑫达医学翻译 发布时间:2014-07-17 8:50:52 阅读:
 

原文:A tubular scaffold composed of polylactide fibres (outside layer) and silk fibroin-gelatin (SF-gelatin) fibres (inner layer) was fabricated successfullyby electrospinning. The graft were chemically treated by immers­ing in 100% ethanol for 15 min and dried for 24 h at room temperature to increase stability and strength. These composite tubular scaffolds showed good biomechanical and biocompatible properties; while the PLA layer was responsible for the mechanical properties, the SF-gelatin layer supported cell growth. The tensile properties of the PLA-SF-gelatin composite scaffolds were significantly dif­ferent from the SF-gelatin alone and PLA alone scaffolds. The suture retention strength of the composite scaffolds in­creased significantly with respect to single polymers and was more than adequate for suturing during implantation (i.e. 2.0 N). After ethanol treatment, burst pressure values increased above the standard value for vascular clinical application, and the dissolvability of the ethanol-treated PLA-SF-gelatin composite scaffolds in water decreased.
 
译文:有研究者利用静电纺丝技术,成功制备了由多乳酸纤维(外层)和蚕丝丝心蛋白-明胶(SF-明胶)纤维(内层)组成的管状支架。将移植物浸入100%乙醇中化学处理15min,室温干燥24h,以增加稳定性和强度。该复合材料管状支架具备良好的生物机械性能和生物相容性,其中PLA层有助于维持机械性能,SF-明胶层支持细胞生长。PLA-SF-明胶复合材料支架的拉伸性能与纯SF-明胶支架和纯PLA支架显著不同。复合材料支架的缝合保留强度相对于单一聚合物显著增加,完全能够用于植入过程中的缝合(如2.0 N)。乙醇处理后,爆破压力值增加,超过了血管临床应用的标准值。乙醇处理后,PLA-SF-明胶复合材料支架在水中的溶解性降低。


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